Question discussion

What should come in place of ‘?’ in the following number series?5, 17, 43, 89, ?

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⇒ 13 + 22 = 1 + 4 = 5

⇒ 23 + 32 = 8 + 9 = 17

⇒ 33 + 42 = 27 + 16 = 43

⇒ 43 + 52 = 64 + 25 = 89

⇒ 53 + 62 = 125 + 36 = 161 = ?